Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314712 | 0.93 | SMN1; SMN2 (0.38) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7317073 | 0.93 | MEN1 (0.33) | GAAALDH1A1MEN1KMT2AACHE | |
| SCHEMBL7317112 | 0.91 | OPRL1 (0.38) | OPRL1ALDH1A1LMNATYR | |
| SCHEMBL7313581 | 0.89 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7315401 | 0.85 | GRIN1 (0.41) | — | |
| SCHEMBL7313690 | 0.85 | CYP1A2 (0.33) | GAAALDH1A1KDM4ELMNA | |
| SCHEMBL7314518 | 0.85 | ALDH1A1 (0.44) | OPRL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7308037 | 0.84 | PKM (0.35) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7304525 | 0.84 | CYP1A2 (0.38) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7313049 | 0.84 | SMN1; SMN2 (0.38) | OPRL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |