Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316021 | 0.97 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7318303 | 0.88 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7314553 | 0.87 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7309450 | 0.85 | MAPT (0.52) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7319188 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7317898 | 0.82 | MAPT (0.53) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7320153 | 0.80 | RAB9A (0.48) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7310463 | 0.78 | SIRT3 (0.39) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7309722 | 0.77 | SIRT3 (0.44) | ALDH1A1KDM4EKMT2AMAPTTDP1 | |
| SCHEMBL21029934 | 0.77 | SIRT5 (0.46) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |