Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316507 | 0.95 | FAAH (0.33) | DRD2DRD3FAAHSIGMAR1 | |
| SCHEMBL7310892 | 0.95 | DRD2 (0.33) | DRD2DRD3HTR2BFAAHSIGMAR1 | |
| SCHEMBL7306960 | 0.94 | GPR119 (0.33) | DRD2DRD3FAAHSIGMAR1 | |
| SCHEMBL7310067 | 0.93 | DRD2 (0.33) | DRD2DRD3FAAH | |
| SCHEMBL7317037 | 0.92 | DRD2 (0.33) | DRD2DRD3HTR2BRORC | |
| SCHEMBL7308728 | 0.91 | SIGMAR1 (0.34) | HTR2BSIGMAR1KCNA3 | |
| SCHEMBL7313311 | 0.91 | FAAH (0.33) | DRD2DRD3FAAHSIGMAR1 | |
| SCHEMBL7310946 | 0.90 | GPR119 (0.33) | DRD2DRD3FAAHSIGMAR1 | |
| SCHEMBL7315494 | 0.90 | SIGMAR1 (0.36) | DRD2HTR2BSIGMAR1 | |
| SCHEMBL7309520 | 0.90 | SIGMAR1 (0.36) | DRD2HTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |