Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310914 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7311759 | 0.83 | LMNA (0.48) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7311755 | 0.83 | LMNA (0.48) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8049631 | 0.79 | MEN1 (0.53) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9432247 | 0.78 | MAPT (0.41) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9432244 | 0.78 | MAPT (0.41) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7300293 | 0.75 | MEN1 (0.49) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL164410 | 0.74 | GPR35 (0.56) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL3354607 | 0.72 | POLB (0.49) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL3354613 | 0.72 | POLB (0.49) | ALDH1A1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |