Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309384 | 0.98 | CHRM2 (0.43) | HTR7CACNA1GCCR3ALDH1A1CHRM2 | |
| SCHEMBL7311744 | 0.96 | HTR7 (0.43) | HTR7CCR3ALDH1A1CHRM2CHRM4 | |
| SCHEMBL7314570 | 0.96 | CACNA1G (0.43) | HTR7CACNA1GCCR3ALDH1A1CHRM2 | |
| SCHEMBL7307606 | 0.94 | CHRM2 (0.43) | HTR7CACNA1GALDH1A1CHRM2CHRM4 | |
| SCHEMBL7312963 | 0.93 | LTA4H (0.48) | HTR7 | |
| SCHEMBL7315052 | 0.92 | ALDH1A1 (0.44) | HTR7CCR3ALDH1A1CHRM2CHRM4 | |
| SCHEMBL7307208 | 0.92 | LTA4H (0.49) | — | |
| SCHEMBL7303537 | 0.91 | LTA4H (0.47) | — | |
| SCHEMBL7310167 | 0.91 | CACNA1G (0.42) | HTR7CACNA1GALDH1A1 | |
| SCHEMBL7309302 | 0.90 | ALDH1A1 (0.44) | CCR3ALDH1A1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |