Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317001 | 0.84 | MAPT (0.31) | MAPTALDH1A1POLB | |
| SCHEMBL7316993 | 0.81 | MAPT (0.34) | MAPTHPGDNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7320601 | 0.80 | PDE3B (0.35) | MAPTHPGDNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7316075 | 0.76 | PDE3B (0.49) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7314546 | 0.74 | PDE3B (0.39) | MAPTHPGDNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7317200 | 0.72 | PDE3B (0.50) | MAPTHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7312638 | 0.70 | MAPT (0.35) | MAPTHPGDNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7316945 | 0.69 | ALDH1A1 (0.36) | MAPTHPGDNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7312241 | 0.68 | MAPT (0.37) | MAPTHPGDNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7316094 | 0.67 | PDE3B (0.45) | MAPTHPGDNPSR1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |