Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.57 |
| ▸ | CCKAR | P32238 | 3/20 | 0.57 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 3/20 | 0.48 |
| ▸ | BRD2 | P25440 | 3/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939498 | 0.79 | SENP1 (0.73) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL9865538 | 0.79 | SENP1 (0.73) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8711261 | 0.78 | SENP1 (0.79) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8939417 | 0.78 | SENP1 (0.79) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8711263 | 0.78 | SENP1 (0.79) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8585550 | 0.78 | CCKBR (0.71) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8585545 | 0.78 | CCKBR (0.71) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8534744 | 0.77 | CCKBR (0.62) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL8534751 | 0.77 | CCKBR (0.62) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL7318234 | 0.77 | GABRP (0.59) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994893-B1 | SELECTIVE FACTOR XA INHIBITORS CONTAINING A FUSED AZEPINONE STRUCTURE | COR THERAPEUTICS INC (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6333321-B1 | FOR THERAPY OF UNSTABLE ANGINA, REFRACTORY ANGINA, MYOCARDIAL INFARCTION, TRANSIENT ISCHEMIC ATTACKS, THROMBOTIC STROKE, EMBOLIC STROKE, DISSEMINATED INTRAVASCULAR COAGULATION, DEEP VENOUS THROMBOSIS, PULMONARY EMBOLISM, AND REOCCLUSION | COR THERAPEUTICS, INC. | 2001-12-25 | — | — | US | disclosed |
| EP-0994893-A1 | SELECTIVE FACTOR XA INHIBITORS CONTAINING A FUSED AZEPINONE STRUCTURE | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007730-A1 | SELECTIVE FACTOR Xa INHIBITORS CONTAINING A FUSED AZEPINONE STRUCTURE | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |