Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326245 | 0.82 | SIGMAR1 (0.44) | TSHRPOLB | |
| SCHEMBL10662835 | 0.81 | CA12 (0.53) | TSHRRAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL19380612 | 0.73 | IDO1 (0.54) | AKR1C3HTTCYP2C9CYP2C19TSHR | |
| SCHEMBL3500363 | 0.73 | CA12 (0.46) | AKR1C3TSHRRAB9ALMNAGAA | |
| SCHEMBL6581393 | 0.72 | CA12 (0.52) | TSHRRAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL6568800 | 0.71 | CA12 (0.55) | TSHRRAB9ALMNAGAAHPGD | |
| SCHEMBL30672091 | 0.71 | CA12 (0.55) | TSHRRAB9ALMNAGAAHPGD | |
| SCHEMBL6195893 | 0.69 | RAB9A (0.56) | HTTTSHRRAB9ALMNAGAA | |
| SCHEMBL30804587 | 0.69 | RAB9A (0.56) | HTTTSHRRAB9ALMNAGAA | |
| SCHEMBL31563193 | 0.68 | CREBBP (0.45) | AKR1C3HTTCYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202760-A2 | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-26 | — | — | EP | claimed |