Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317306 | 0.87 | HSD11B1 (0.39) | HTR6ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7312016 | 0.84 | HRH3 (0.40) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL11070246 | 0.72 | DRD4 (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7317014 | 0.72 | MAOA (0.41) | ALDH1A1GAATSHRPOLBALOX15 | |
| SCHEMBL10567416 | 0.71 | SIGMAR1 (0.54) | — | |
| SCHEMBL11362472 | 0.70 | HTR6 (0.41) | HTR6GAATSHRKMT2ALOXL2 | |
| SCHEMBL7312087 | 0.69 | MCL1 (0.39) | ALDH1A1GAATSHRALOX15MEN1 | |
| SCHEMBL7307694 | 0.68 | PDE3B (0.45) | ALDH1A1TSHRALOX15MEN1KMT2A | |
| SCHEMBL7307700 | 0.68 | PDE3B (0.45) | ALDH1A1TSHRALOX15MEN1KMT2A | |
| SCHEMBL15110117 | 0.68 | ALDH1A1 (0.48) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |