Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322549 | 0.91 | SIGMAR1 (0.48) | HRH3SIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL7323139 | 0.85 | HRH3 (0.42) | HRH3SIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL7323050 | 0.85 | HRH3 (0.53) | HRH3SIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL7315840 | 0.81 | CEL (0.38) | SIGMAR1 | |
| SCHEMBL7325823 | 0.81 | SIGMAR1 (0.47) | HRH3SIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL7312887 | 0.80 | FFAR1 (0.44) | — | |
| SCHEMBL7323813 | 0.79 | SIGMAR1 (0.46) | HRH3SIGMAR1MEN1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL7315858 | 0.78 | FFAR1 (0.43) | — | |
| SCHEMBL7316201 | 0.78 | ALDH1A1 (0.47) | HRH3SIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL27468862 | 0.77 | HRH3 (0.50) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |