Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR1D | P28221 | 3/20 | 0.48 |
| ▸ | HTR1B | P28222 | 3/20 | 0.48 |
| ▸ | HTR1F | P30939 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7320940 | 0.89 | HTR6 (0.70) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL7319385 | 0.83 | HTR6 (0.66) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3029775 | 0.81 | PPARG (0.62) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL7436342 | 0.81 | HTR6 (0.73) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL7314748 | 0.80 | HTR6 (0.49) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL7314759 | 0.79 | HTR6 (0.60) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Oxalic Acid SCHEMBL7436726 | 0.79 | HTR6 (0.69) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Oxalic Acid SCHEMBL7433702 | 0.78 | HTR6 (0.90) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL7316956 | 0.78 | HTR6 (0.64) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL7318955 | 0.78 | HTR6 (0.61) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | HTR6 4503/4885HTR1A 4812/4885HTR1D 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.