Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457530 | 0.81 | KAT2B (0.36) | ALDH1A1 | |
| SCHEMBL6206141 | 0.81 | ALDH1A1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL8507244 | 0.81 | TSHR (0.30) | TSHR | |
| SCHEMBL9008022 | 0.81 | CYP1A2 (0.30) | TSHR | |
| SCHEMBL9653209 | 0.79 | ALOX5 (0.38) | TSHRALDH1A1 | |
| SCHEMBL27357221 | 0.79 | TDP1 (0.32) | TSHR | |
| SCHEMBL10746021 | 0.79 | TAAR1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL11153835 | 0.77 | MAPT (0.33) | ALDH1A1 | |
| SCHEMBL27398680 | 0.77 | FAAH (0.38) | TSHRALDH1A1 | |
| SCHEMBL591107 | 0.77 | PYCR1 (0.35) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |
| EP-0542372-A1 | 2-Substituted saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | claimed |
| EP-0094727-A2 | Substituted heterocyclyl phenylformamidines, processes for their preparation and their pharmaceutical use | ISTITUTO DE ANGELI S.p.A. (IT) | 1983-11-23 | — | — | EP | disclosed |