Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27357221 | 0.86 | TDP1 (0.32) | TSHR | |
| SCHEMBL457530 | 0.81 | KAT2B (0.36) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7314015 | 0.81 | TSHR (0.49) | TSHR | |
| SCHEMBL8507244 | 0.81 | TSHR (0.30) | TSHR | |
| SCHEMBL6206141 | 0.81 | ALDH1A1 (0.37) | CYP2C19TSHR | |
| SCHEMBL591107 | 0.81 | PYCR1 (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL10746021 | 0.79 | TAAR1 (0.35) | CYP1A2CYP2D6TSHR | |
| SCHEMBL9653209 | 0.79 | ALOX5 (0.38) | TSHR | |
| SCHEMBL27931297 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL27398680 | 0.77 | FAAH (0.38) | CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | claimed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | claimed |
| CN-112638909-A | Compounds with antibacterial activity | 香港理工大学 | 2021-04-09 | — | — | CN | disclosed |
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | disclosed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | disclosed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | disclosed |