Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733527 | 0.83 | — | — | |
| SCHEMBL732540 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL731439 | 0.79 | CES2 (0.35) | HSD17B10CES2 | |
| SCHEMBL15290248 | 0.73 | HSD17B10 (0.34) | HSD17B10CES2 | |
| SCHEMBL12106714 | 0.73 | — | — | |
| SCHEMBL733391 | 0.73 | — | — | |
| SCHEMBL12123165 | 0.71 | — | — | |
| SCHEMBL658040 | 0.70 | — | — | |
| SCHEMBL11851237 | 0.70 | — | — | |
| SCHEMBL733399 | 0.70 | ALDH1A1 (0.39) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138118-B2 | Plant safening agents ; side effect reduction of pesticides, herbicides, insecticides, fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-7838463-B2 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-23 | — | — | US | disclosed |
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2005-03-03 | — | — | US | disclosed |
| US-20050037922-A1 | Use of hydroxyaromatics as safeners | BAYER CROPSCIENCE GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20040224844-A1 | Use of hydroxyaromatic compounds as safeners | BAYER CROPSCIENCE GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050037922-A1 | Use of hydroxyaromatics as safeners | CBR1, CYP8B1, AHR | HSD17B10 143/4885CES2 616/4885 |
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | GRHPR, HCAR1, HCAR3 | HSD17B10 241/4885CES2 494/4885 |
| US-20040224844-A1 | Use of hydroxyaromatic compounds as safeners | CBR1, CYC1, NR2E1 | HSD17B10 265/4885CES2 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.