SCHEMBL731491

SCHEMBL731491

N#CC(C#N)=C1C2=C(C=CCC2=O)c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
ALDH1A1 P00352 1/20 0.34
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 1/20 0.34
GPR35 Q9HC97 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10900576 0.77 MAOA (0.36) MAPTKDM4EKMT2A
SCHEMBL28829617 0.76 MAOA (0.36) MAPTKDM4EKMT2A
SCHEMBL28031911 0.74 MAPT (0.31) MAPTALDH1A1KDM4E
SCHEMBL1501865 0.74 CDC25B (0.41) MAPTALDH1A1KDM4EKMT2A
SCHEMBL10721373 0.72 MAPT (0.32) MAPTALDH1A1KDM4E
SCHEMBL16579336 0.71 MAPT (0.39) MAPTALDH1A1KDM4EKMT2AGPR35
SCHEMBL28310749 0.70 SMN1; SMN2 (0.35) MAPTALDH1A1KDM4EKMT2A
Terephthalamide SCHEMBL27579267 0.69 PARP10 (0.41) MAPTALDH1A1KMT2A
SCHEMBL10654735 0.68 MEN1 (0.52) MAPTALDH1A1KDM4EKMT2AEGFR
SCHEMBL3829679 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142647-B2 For making ultra low sulfur fuels; adsorbent which is silica functionalized with 2,4,5,7-tetranitro-9-fluorenylideneaminooxy propionic acid is contacted with aromatic compound, a dibenzothiophene compound, and an aliphatic solvent; regenerating the adsorbent with toluene CHEVRON U.S.A. INC. (US) 2012-03-27 US disclosed
US-8138369-B2 Removal of branched dibenzothiophenes from hydrocarbon mixtures via charge transfer complexes with a TAPA-functionalized adsorbent CHEVRON U.S.A. INC. (US) 2012-03-20 US disclosed
WO-2010074894-A2 ADSORPTION OF DIBENZOTHIOPHENES FROM HYDROCARBON AND MODEL DIESEL FEEDS CHEVRON U.S.A. INC. (US) 2010-07-01 WO disclosed
US-20100147748-A1 ADSORPTION OF DIBENZOTHIOPHENES FROM HYDROCARBON AND MODEL DIESEL FEEDS CHEVRON U.S.A. INC. 2010-06-17 US disclosed
US-20090076221-A1 REMOVAL OF BRANCHED DIBENZOTHIOPHENES FROM HYDROCARBON MIXTURES VIA CHARGE TRANSFER COMPLEXES WITH A TAPA-FUNCTIONALIZED ADSORBENT CHEVRON U.S.A. INC. 2009-03-19 US disclosed
WO-2008154331-A1 REMOVAL OF BRANCHED DIBENZOTHIOPHENES FROM HYDROCARBON MIXTURES VIA CHARGE TRANSFER COMPLEXES WITH A TAPA-FUNCTIONALIZED ADSORBENT CHEVRON U.S.A. INC. (US) 2008-12-18 WO disclosed
EP-0642680-B1 PHOTOCONDUCTIVE RECORDING MATERIAL COMPRISING A CROSSLINKED BINDER SYSTEM XEIKON NV (BE) 2001-07-04 EP disclosed
US-6174635-B1 COMPRISING CONDUCTIVE SUPPORT AND PHOTOSENSITIVE LAYER CONTAINING PHOTOCONDUCTIVE CRYSTALLINE SUBSTITUTED METAL-FREE PHTHALOCYANINE COMPOUND AND/OR MIXED CRYSTALS OF SUBSTITUTED AND SUBSTITUTED METAL FREE PHTHALOCYANINE COMPOUNDS AGFA-GEVAERT, N.V. (BE) 2001-01-16 US disclosed
US-5786118-A METHYLENE CHLORIDE CROSSLINKER; INSOLUBILITY AGFA-GEVAERT, N.V. (BE) 1998-07-28 US disclosed
US-5721080-A Electrophotographic material containing particular phthalocyanines AGFA-GEVAERT, N.V. (BE) 1998-02-24 US disclosed
US-4990421-A High charge generating compound from diazonium salt and aromatic hydroxyamide or imide coupler AGFA-GEVAERT, N.V. (BE) 1991-02-05 US disclosed
US-4981768-A Photosensitive recording material having an N-aryl carbazole p-type charge transport compound AGFA-GEVAERT, N.V. (BE) 1991-01-01 US disclosed
EP-0388531-A1 Recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1990-09-26 EP disclosed
US-4943502-A TWO LAYER SYSTEM OF CHARGE GENERATING AND CHARGE TRANSPORTING COMPOUNDS AGFA-GEVAERT, N.V. (BE) 1990-07-24 US disclosed
US-4923774-A Layered electrophotographic recording element comprising p-type charge transport compounds AGFA-GEVAERT, N.V. (BE) 1990-05-08 US disclosed
EP-0350984-A1 Electrophotographic recording material containing a trisazo dye AGFA-GEVAERT N.V. (BE) 1990-01-17 EP disclosed
EP-0349034-A1 Electrophotographic recording material AGFA-GEVAERT N.V. (BE) 1990-01-03 EP disclosed
EP-0347960-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed
EP-0347967-A1 Photosensitive recording material suited for use in electrophotography AGFA-GEVAERT N.V. (BE) 1989-12-27 EP disclosed
EP-0034497-B1 ELECTROPHOTOGRAPHIC LIGHT-SENSITIVE MEDIA Canon Inc. (JP) 1985-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076221-A1 REMOVAL OF BRANCHED DIBENZOTHIOPHENES FROM HYDROCARBON MIXTURES VIA CHARGE TRANSFER COMPLEXES WITH A TAPA-FUNCTIONALIZED ADSORBENT TST, SLC43A1, BCAT1 MAPT 1225/4885ALDH1A1 566/4885KDM4E 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.