Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317403 | 0.90 | METAP2 (0.48) | FFAR4GABRG2GABRB3GABRA3GAA | |
| SCHEMBL7311131 | 0.90 | FFAR4 (0.44) | FFAR4GABRG2GABRB3GABRA3GAA | |
| SCHEMBL7313794 | 0.86 | MTNR1A (0.42) | GAAMEN1KMT2AMMP1MMP13 | |
| SCHEMBL7314226 | 0.86 | FFAR4 (0.43) | FFAR4GABRG2GABRB3GABRA3GAA | |
| SCHEMBL7317686 | 0.86 | FFAR4 (0.51) | FFAR4GABRG2GABRB3GABRA3GAA | |
| SCHEMBL7322650 | 0.83 | METAP2 (0.58) | FFAR4GABRG2GABRB3GABRA3GAA | |
| SCHEMBL7316525 | 0.83 | ALDH1A1 (0.42) | GAAMEN1KMT2AL3MBTL1MMP1 | |
| SCHEMBL7325564 | 0.82 | METAP2 (0.49) | FFAR4GABRG2GABRB3GABRA3GAA | |
| SCHEMBL7318301 | 0.82 | MTNR1A (0.43) | FFAR4GAAMEN1KMT2ATP53 | |
| SCHEMBL7321197 | 0.80 | MTNR1A (0.41) | FFAR4GAAMEN1KMT2ACYTH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |