Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311139 | 0.86 | EBP (0.43) | L3MBTL1CYP3A4ADRA1AADRA1DADRA1B | |
| SCHEMBL7313653 | 0.86 | EBP (0.43) | L3MBTL1CYP3A4ADRA1AADRA1DADRA1B | |
| SCHEMBL7315211 | 0.82 | POLB (0.39) | L3MBTL1EPHX2CYP3A4ADRA1AADRA1D | |
| SCHEMBL7314600 | 0.82 | GPR139 (0.39) | L3MBTL1THRBCYP3A4ADRA1AADRA1D | |
| SCHEMBL7309023 | 0.80 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1HPGDGAA | |
| SCHEMBL7308820 | 0.80 | CYP3A4 (0.38) | L3MBTL1CYP3A4ADRA1AADRA1DADRA1B | |
| SCHEMBL7309649 | 0.78 | MTNR1A (0.43) | KCNH2CYP3A4ADRA1A | |
| SCHEMBL7315392 | 0.75 | BLM (0.41) | L3MBTL1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL7313591 | 0.74 | CCR1 (0.39) | ADRA1AADRA1DADRA1BHDAC6ALDH1A1 | |
| SCHEMBL5240595 | 0.73 | L3MBTL1 (0.41) | L3MBTL1SLC22A2SLC22A1PGRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |