Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.58 |
| ▸ | HTR2A | P28223 | 8/20 | 0.58 |
| ▸ | HTR1B | P28222 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | MPO | P05164 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325860 | 0.83 | LTA4H (0.59) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| Hydrochloric Acid SCHEMBL7312565 | 0.82 | LTA4H (0.61) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| SCHEMBL7334745 | 0.81 | HTR1D (0.64) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| SCHEMBL2536567 | 0.79 | LTA4H (0.67) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| SCHEMBL7325323 | 0.78 | HTR2A (0.77) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| SCHEMBL27596004 | 0.75 | HTR2A (0.59) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| Hydrochloric Acid SCHEMBL7313598 | 0.75 | LTA4H (0.65) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| SCHEMBL1129793 | 0.74 | HTR1D (1.00) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| SCHEMBL30867163 | 0.74 | HTR1D (1.00) | HTR1DHTR2AHTR1BHTR2CCYP1A2 | |
| Hydrochloric Acid SCHEMBL7318059 | 0.74 | PMP22 (0.51) | HTR1DHTR2AHTR1BHTR2CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | HTR1D 4756/4885HTR2A 4799/4885HTR1B 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.