SCHEMBL7315921

SCHEMBL7315921

CN(CCc1ccccc1)C(=O)C1CC1c1ccc(C2CCCCC2)c(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.41
F2 P00734 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
SLC6A3 Q01959 1/20 0.37
SLC6A4 P31645 1/20 0.36
SLC18A3 Q16572 1/20 0.36
GPR88 Q9GZN0 1/20 0.36
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
ACKR3 P25106 2/20 0.35
NPY2R P49146 2/20 0.35
FFAR4 Q5NUL3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7323035 0.90 SLC6A4 (0.43) APPL3MBTL1KDM4ESLC6A3SLC6A4
SCHEMBL7321171 0.80 GPR88 (0.44) GPR88
SCHEMBL7320685 0.79 SIGMAR1 (0.42) GPR88
SCHEMBL7322425 0.79 SLC6A4 (0.41) SLC6A3SLC6A4SLC18A3OPRM1OPRD1
SCHEMBL7323813 0.78 SIGMAR1 (0.46) APP
SCHEMBL7312887 0.77 FFAR1 (0.44)
SCHEMBL7324009 0.76 SIGMAR1 (0.44) F2L3MBTL1KDM4ESLC6A4
SCHEMBL7324686 0.76 CNR2 (0.39) SLC6A3SLC6A4OPRM1OPRD1
Hydrochloric Acid SCHEMBL7315858 0.76 FFAR1 (0.43)
SCHEMBL7315840 0.76 CEL (0.38) SLC6A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1154483-C Use of amines to produce drugs for preventing tumour cell proliferation ��ŵ��-ʥ�������ɷ����޹�˾ 2004-06-23 CN disclosed
US-6235791-B1 USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE SANOFI-SYNTHELABO (FR) 2001-05-22 US disclosed
CN-1226825-A Use of amines to produce drugs for preventing tumour cell proliferation SANOFI SA (FR) 1999-08-25 CN disclosed