Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670929 | 0.77 | ALOX15 (0.41) | ALOX15KMT2A | |
| SCHEMBL38660994 | 0.77 | ALOX15 (0.41) | ALOX15KMT2A | |
| SCHEMBL22072451 | 0.76 | KMT2A (0.42) | ALOX15KMT2ACYP2A6UHRF1 | |
| SCHEMBL28559148 | 0.76 | ALOX15 (0.36) | ALOX15KMT2ACYP2A6UHRF1 | |
| Hydrochloric Acid SCHEMBL22042734 | 0.74 | KMT2A (0.41) | ALOX15KMT2ACYP2A6 | |
| SCHEMBL108078 | 0.72 | P2RX7 (0.36) | ALOX15KMT2A | |
| SCHEMBL23747677 | 0.69 | ALOX15 (0.37) | ALOX15KMT2AUHRF1 | |
| SCHEMBL882969 | 0.69 | SORD (0.45) | ALOX15KMT2A | |
| SCHEMBL1578222 | 0.69 | KMO (0.51) | ALOX15KMT2A | |
| SCHEMBL2465653 | 0.68 | KMT2A (0.50) | ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |