Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555576 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL734469 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL375876 | 0.76 | — | — | |
| SCHEMBL23521422 | 0.74 | — | — | |
| SCHEMBL1702223 | 0.73 | — | — | |
| SCHEMBL8464619 | 0.72 | — | — | |
| SCHEMBL5418098 | 0.71 | — | — | |
| SCHEMBL55703 | 0.71 | — | — | |
| SCHEMBL612550 | 0.70 | — | — | |
| SCHEMBL29923856 | 0.70 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138365-B2 | Method for producing organosilanes | EVONIK DEGUSSA GMBH (DE) | 2012-03-20 | — | — | US | claimed |
| US-20100217026-A1 | Method for producing organosilanes | EVONIK OPERATIONS GMBH (DE) | 2010-08-26 | — | — | US | claimed |
| EP-2057172-B1 | METHOD FOR PRODUCING ORGANOSILANES | EVONIK DEGUSSA GMBH (DE) | 2013-09-11 | — | — | EP | disclosed |
| CN-101511848-B | Method for producing organosilanes | EVONIK DEGUSSA GMBH | 2012-08-29 | — | — | CN | disclosed |
| US-8138365-B2 | Method for producing organosilanes | EVONIK DEGUSSA GMBH (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100217026-A1 | Method for producing organosilanes | EVONIK OPERATIONS GMBH (DE) | 2010-08-26 | — | — | US | disclosed |
| CN-101511848-A | Method for producing organosilanes | EVONIK DEGUSSA GMBH (DE) | 2009-08-19 | — | — | CN | disclosed |
| EP-0676403-B1 | Arylaminosilane end-capped urethane sealants | WITCO CORP (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0586241-B1 | Azasilacycloalkyl functional alkoxysilanes and azasilacycloalkyl functional tetramethyldisiloxanes | DOW CORNING (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0586240-B1 | Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom | DOW CORNING (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0499407-B1 | Crosslinkers and chain extenders for room temperature vulcanization or crosslinking of polymers | DOW CORNING (US) | 1996-10-02 | — | — | EP | disclosed |
| EP-0586240-A2 | Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom | DOW CORNING CORPORATION (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5276123-A | Endblocking polysiloxanes | DOW CORNING CORPORATION (US) | 1994-01-04 | — | — | US | disclosed |
| US-5239099-A | Room temperature vulcanization; noncorrosive byproducts | DOW CORNING CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |
| US-5238988-A | Rapid cure room temperature vulcanizable organosiloxane compositions | DOW CORNING CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |
| US-5162560-A | Chemical intermediates | DOW CORNING CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0499409-A1 | Olefinic and acetylenic azasilacyclopentanes | DOW CORNING CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| EP-0499407-A1 | Crosslinkers and chain extenders for room temperature vulcanization or crosslinking of polymers | DOW CORNING CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5136064-A | Reacting organosilicon compound with grignard reagent in presence of ether, then acetyl chloride and lewis acid and amine | DOW CORNING CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5110967-A | No evolution of volatile by-products; sealants | DOW CORNING CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100217026-A1 | Method for producing organosilanes | TST, STS, HAO2 | MAPK1 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.