SCHEMBL734469

SCHEMBL734469

CCOC(OCC)[SiH2]CC(C)CCl

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL612550 0.83
SCHEMBL375599 0.78 LMNA (0.35) LMNATHRB
SCHEMBL731628 0.77 MAPK1 (0.31)
SCHEMBL10969309 0.77
SCHEMBL22346066 0.77 LMNA (0.41) LMNATHRB
SCHEMBL56821 0.74 THRB (0.38) LMNATHRB
SCHEMBL734012 0.71 THRB (0.39) LMNATHRB
SCHEMBL55696 0.70 THRB (0.35) LMNATHRB
SCHEMBL8464619 0.69
SCHEMBL9241853 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US claimed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US claimed
EP-2057172-B1 METHOD FOR PRODUCING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2013-09-11 EP disclosed
CN-101511848-B Method for producing organosilanes EVONIK DEGUSSA GMBH 2012-08-29 CN disclosed
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US disclosed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US disclosed
CN-101511848-A Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2009-08-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217026-A1 Method for producing organosilanes TST, STS, HAO2 LMNA 4751/4885THRB 2259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.