Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309076 | 0.92 | ALDH1A1 (0.39) | CHRM2CHRM1ALDH1A1KCNH2SCN5A | |
| SCHEMBL7310439 | 0.91 | CHRM2 (0.39) | CHRM2CHRM1ALDH1A1LMNATP53 | |
| SCHEMBL7311690 | 0.86 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2TP53L3MBTL1KDM4E | |
| SCHEMBL7311851 | 0.85 | STS (0.38) | CHRM2CHRM1ALDH1A1TP53MAPT | |
| SCHEMBL7304874 | 0.84 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL7303836 | 0.83 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL7311024 | 0.81 | SMN1; SMN2 (0.35) | CHRM2CHRM1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7314659 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTRECQLKDM4E | |
| SCHEMBL7314564 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNATP53MAPTL3MBTL1 | |
| SCHEMBL7307905 | 0.78 | FKBP1A (0.32) | SMN1; SMN2MAPK1L3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |