Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311024 | 0.95 | SMN1; SMN2 (0.35) | SMN1; SMN2TP53ALDH1A1ACHEL3MBTL1 | |
| SCHEMBL7307905 | 0.91 | FKBP1A (0.32) | SMN1; SMN2L3MBTL1TSHRCCR5 | |
| SCHEMBL7303836 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2TP53ALDH1A1KDM4ETSHR | |
| SCHEMBL7304874 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53ALDH1A1KDM4ETSHR | |
| SCHEMBL7305450 | 0.88 | CCR5 (0.35) | SMN1; SMN2TP53ALDH1A1ACHEL3MBTL1 | |
| SCHEMBL7316429 | 0.86 | CHRM2 (0.38) | SMN1; SMN2TP53ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7314659 | 0.85 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KDM4EACHETSHR | |
| SCHEMBL7314564 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2TP53L3MBTL1CCR5 | |
| SCHEMBL7303493 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1ACHEL3MBTL1TSHR | |
| SCHEMBL7306902 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2TP53ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |