Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311690 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2CCR5L3MBTL1TSHR | |
| SCHEMBL7311024 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2CCR5L3MBTL1TSHR | |
| SCHEMBL7310309 | 0.88 | ITGB3 (0.34) | RECQLSMN1; SMN2CCR5L3MBTL3L3MBTL1 | |
| SCHEMBL7302535 | 0.88 | HRH3 (0.34) | SIGMAR1TSHR | |
| SCHEMBL7313319 | 0.88 | MTOR (0.32) | MTOR | |
| SCHEMBL7309076 | 0.84 | ALDH1A1 (0.39) | RECQLL3MBTL1MAPK1 | |
| SCHEMBL7303568 | 0.84 | ALDH1A1 (0.45) | FKBP1ARECQLSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL7305450 | 0.83 | CCR5 (0.35) | SMN1; SMN2CCR5L3MBTL3L3MBTL1MAPK1 | |
| SCHEMBL7303493 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2CCR5OPRM1L3MBTL1TSHR | |
| SCHEMBL7303836 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2CCR5OPRM1OPRL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |