Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308778 | 0.94 | LTA4H (0.42) | ACHEBCHELTA4H | |
| SCHEMBL7308443 | 0.92 | ACHE (0.46) | ACHEBCHELTA4H | |
| SCHEMBL7309485 | 0.91 | ALDH1A1 (0.41) | ACHEBCHEKMT2AHTR1AHTR7 | |
| SCHEMBL7316859 | 0.90 | ACHE (0.43) | ACHEBCHE | |
| SCHEMBL7309705 | 0.90 | LTA4H (0.47) | ACHEBCHELTA4H | |
| SCHEMBL7309506 | 0.89 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL7317129 | 0.89 | KMT2A (0.45) | ACHEKMT2AHTR1AHTR7 | |
| SCHEMBL7304426 | 0.89 | LTA4H (0.47) | ACHEBCHELTA4H | |
| SCHEMBL7307268 | 0.88 | LMNA (0.40) | ACHEBCHE | |
| SCHEMBL7307606 | 0.87 | CHRM2 (0.43) | KMT2AHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |