Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518117 | 0.81 | KDM4E (0.41) | REN | |
| SCHEMBL9068826 | 0.81 | KDM4E (0.41) | REN | |
| SCHEMBL9442934 | 0.81 | REN (0.59) | REN | |
| SCHEMBL7361787 | 0.81 | REN (0.59) | REN | |
| SCHEMBL9836878 | 0.80 | MMP8 (0.49) | REN | |
| SCHEMBL7328676 | 0.79 | REN (0.62) | REN | |
| SCHEMBL7323062 | 0.79 | REN (0.62) | REN | |
| SCHEMBL9833483 | 0.79 | REN (0.62) | REN | |
| SCHEMBL9494667 | 0.78 | OPRD1 (0.55) | REN | |
| SCHEMBL6163791 | 0.78 | OPRD1 (0.55) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437508-A4 | NON-PEPTIDE RENIN INHIBITORS | — | 1991-11-06 | — | — | EP | disclosed |
| EP-0437508-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1991-07-24 | — | — | EP | disclosed |
| WO-1990003971-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-04-19 | — | — | WO | disclosed |