Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934076 | 0.88 | PTGS1 (0.54) | PTGS1PTGS2PDPK1 | |
| SCHEMBL23358701 | 0.84 | PTGS1 (0.53) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL950143 | 0.83 | PTGS1 (0.64) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL6343163 | 0.83 | PTGS2 (0.67) | PTGS1PTGS2TSHRPDPK1 | |
| SCHEMBL7315950 | 0.83 | ALDH1A1 (0.56) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL25873702 | 0.83 | ALDH1A1 (0.56) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL15919511 | 0.83 | PTGS1 (0.49) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL30677019 | 0.83 | PTGS2 (0.53) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL17064914 | 0.83 | PTGS1 (0.64) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL3276806 | 0.80 | PTGS1 (0.79) | PTGS1PTGS2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | PTGS1 197/4885PTGS2 158/4885ALDH1A1 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.