Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 8/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321778 | 0.91 | ECE1 (0.43) | ECE1KDM4EHPGDHSD17B10TUBB4A | |
| SCHEMBL7317687 | 0.70 | ECE1 (1.00) | ECE1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL7322148 | 0.68 | ECE1 (0.77) | ECE1GPR35ALOX15ALDH1A1KDM4E | |
| SCHEMBL7323063 | 0.68 | ECE1 (1.00) | ECE1GPR35ALOX15P4HTMALDH1A1 | |
| SCHEMBL7308033 | 0.68 | ECE1 (1.00) | ECE1GPR35ALOX15KDM4E | |
| SCHEMBL7321772 | 0.60 | ECE1 (0.82) | ECE1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL7318992 | 0.59 | ECE1 (0.79) | ECE1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL7322763 | 0.59 | ECE1 (0.79) | ECE1KDM4EHPGDHSD17B10 | |
| SCHEMBL7321910 | 0.59 | ECE1 (0.60) | ECE1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27843666 | 0.59 | GPR35 (0.49) | ECE1GPR35ALOX15TPMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891892-A | Small molecule biaryl compounds as inhibitors of endothelin converting enzyme | WARNER-LAMBERT COMPANY (US) | 1999-04-06 | — | — | US | disclosed |