Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312406 | 0.89 | PDE3B (0.43) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7304090 | 0.87 | KDM4E (0.43) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7341497 | 0.86 | PDE3B (0.43) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7307939 | 0.84 | PDE3B (0.41) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7316070 | 0.83 | ALDH1A1 (0.43) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7307393 | 0.83 | PDE3B (0.58) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7310025 | 0.83 | PKM (0.44) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7303943 | 0.83 | ALDH1A1 (0.53) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7317529 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1HPGDTSHR | |
| SCHEMBL7309366 | 0.82 | HSD11B1 (0.44) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56046810-A | — | — | None | — | — | JP | disclosed |
| JP-55035019-A | — | — | None | — | — | JP | disclosed |
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |
| JP-S5646810-A | BLOOD PLATELET COAGULATION INHIBITOR | OTSUKA PHARMACEUT CO LTD | 1981-04-28 | — | — | JP | disclosed |
| JP-S5535019-A | CARBOSTYRYL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1980-03-11 | — | — | JP | disclosed |