Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 13/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 10/20 | 0.45 |
| ▸ | MMP1 | P03956 | 9/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322223 | 0.83 | NAMPT (0.48) | NAMPTMMP9MMP2ALDH1A1MMP13 | |
| SCHEMBL7410712 | 0.83 | MMP9 (0.50) | NAMPTMMP9MMP2ALDH1A1MMP13 | |
| SCHEMBL7314523 | 0.74 | NAMPT (0.55) | NAMPTMMP9ALDH1A1MMP13MMP1 | |
| SCHEMBL7322218 | 0.74 | NAMPT (0.55) | NAMPTMMP9ALDH1A1MMP13MMP1 | |
| SCHEMBL7318032 | 0.71 | NAMPT (0.51) | NAMPTMMP9ALDH1A1MMP13MMP1 | |
| SCHEMBL7311380 | 0.70 | NAMPT (0.48) | NAMPTMMP9MMP2ALDH1A1MMP13 | |
| SCHEMBL7319935 | 0.70 | NAMPT (0.48) | NAMPTMMP9MMP2ALDH1A1MMP13 | |
| SCHEMBL7325350 | 0.70 | NAMPT (0.49) | NAMPTMMP9MMP2ALDH1A1MMP13 | |
| SCHEMBL7324058 | 0.70 | NAMPT (0.49) | NAMPTMMP9ALDH1A1MMP13MMP1 | |
| SCHEMBL13571158 | 0.69 | MMP9 (0.51) | NAMPTMMP9MMP2ALDH1A1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |