Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 12/20 | 0.40 |
| ▸ | MMP9 | P14780 | 12/20 | 0.40 |
| ▸ | MMP12 | P39900 | 11/20 | 0.40 |
| ▸ | MMP13 | P45452 | 11/20 | 0.40 |
| ▸ | MMP8 | P22894 | 10/20 | 0.40 |
| ▸ | MMP14 | P50281 | 9/20 | 0.40 |
| ▸ | MMP16 | P51512 | 9/20 | 0.40 |
| ▸ | MMP3 | P08254 | 6/20 | 0.40 |
| ▸ | MMP1 | P03956 | 6/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316579 | 0.92 | KDM4E (0.44) | KDM4EASPHKDM8MMP2MMP9 | |
| SCHEMBL7322791 | 0.90 | MMP9 (0.41) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL7311156 | 0.86 | KDM4E (0.44) | KDM4EASPHKDM8MMP2MMP9 | |
| SCHEMBL7349832 | 0.83 | MMP9 (0.41) | MMP2MMP9MMP12MMP13MMP8 | |
| SCHEMBL7317521 | 0.83 | MMP13 (0.41) | KDM4EMMP2MMP9MMP12MMP13 | |
| SCHEMBL7322262 | 0.83 | LMNA (0.43) | KDM4EMMP2MMP9MMP12MMP13 | |
| SCHEMBL7322032 | 0.82 | MMP13 (0.40) | KDM4EMMP2MMP9MMP12MMP13 | |
| SCHEMBL7316350 | 0.82 | MMP1 (0.42) | KDM4EASPHKDM8MMP2MMP9 | |
| SCHEMBL7325340 | 0.81 | HCAR2 (0.47) | KDM4EASPHKDM8MMP2MMP9 | |
| SCHEMBL7316215 | 0.81 | MMP13 (0.41) | KDM4EMMP2MMP9MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |