Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315762 | 0.85 | LMNA (0.44) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7312024 | 0.85 | THRA (0.44) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7312020 | 0.82 | LMNA (0.46) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7315787 | 0.82 | LMNA (0.46) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7308459 | 0.80 | THRA (0.44) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7312450 | 0.77 | LMNA (0.44) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7309041 | 0.76 | LMNA (0.43) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7319873 | 0.76 | THRA (0.44) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7318314 | 0.75 | THRA (0.43) | LMNASMN1; SMN2NPSR1THRATHRB | |
| SCHEMBL7319372 | 0.74 | ALDH1A1 (0.47) | LMNASMN1; SMN2THRATHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |