Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320112 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BF2TMPRSS6ALDH1A1 | |
| SCHEMBL7352327 | 0.88 | ITGB3 (0.60) | ITGB3ITGA2BALDH1A1KMT2AMMP1 | |
| SCHEMBL7323685 | 0.85 | LMNA (0.47) | ITGB3ITGA2BLMNATSHRALDH1A1 | |
| SCHEMBL7386244 | 0.85 | ITGB3 (0.79) | ITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL8189053 | 0.79 | MMP2 (0.52) | ITGB3ITGA2BLMNAALDH1A1KMT2A | |
| SCHEMBL7389600 | 0.78 | ITGB3 (0.76) | ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7351137 | 0.78 | ITGB3 (0.63) | ITGB3ITGA2BKMT2A | |
| SCHEMBL7357410 | 0.77 | ITGB3 (0.68) | ITGB3ITGA2B | |
| SCHEMBL7436661 | 0.77 | ITGB3 (0.74) | ITGB3ITGA2BMMP1MMP2MMP3 | |
| SCHEMBL7378671 | 0.76 | ITGB3 (0.76) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | claimed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | claimed |
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |