Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.61 |
| ▸ | PLAU | P00749 | 3/20 | 0.49 |
| ▸ | HPN | P05981 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318568 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BF2TMPRSS6ALDH1A1 | |
| SCHEMBL7351137 | 0.87 | ITGB3 (0.63) | ITGB3ITGA2BPLAUHPN | |
| SCHEMBL7320119 | 0.85 | RAB9A (0.43) | ITGB3ITGA2BRAB9AALDH1A1 | |
| SCHEMBL7389600 | 0.80 | ITGB3 (0.76) | ITGB3ITGA2B | |
| SCHEMBL7323474 | 0.80 | F10 (0.47) | ITGB3ITGA2BPLAUHPNF2 | |
| SCHEMBL7357410 | 0.79 | ITGB3 (0.68) | ITGB3ITGA2B | |
| SCHEMBL7378671 | 0.78 | ITGB3 (0.76) | ITGB3ITGA2B | |
| SCHEMBL7348953 | 0.78 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL7353684 | 0.78 | ITGB3 (0.63) | ITGB3ITGA2BF2TMPRSS6 | |
| SCHEMBL7352327 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | claimed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | claimed |
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |