Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319529 | 0.80 | MMEL1 (0.39) | MMEL1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL7314865 | 0.77 | MMEL1 (0.38) | MMEL1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL7318595 | 0.77 | L3MBTL1 (0.41) | MMEL1L3MBTL1MAPTRAB9A | |
| SCHEMBL7319618 | 0.76 | PPID (0.37) | CYP3A4CYP2D6CYP2C19MAPTRAB9A | |
| Benzoic Acid SCHEMBL7322120 | 0.76 | PTGES (0.39) | MMEL1MAPT | |
| SCHEMBL7311117 | 0.76 | MMEL1 (0.37) | MMEL1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL7318805 | 0.76 | MMEL1 (0.37) | MMEL1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL7343809 | 0.75 | MMEL1 (0.50) | MMEL1 | |
| SCHEMBL7311798 | 0.75 | HDAC3 (0.37) | MMEL1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9681904 | 0.75 | MMEL1 (0.39) | MMEL1L3MBTL1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |