Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7307989 | 0.99 | GRIN2B (0.49) | GRIN2BCRBNALDH1A1KMT2AHTR1A | |
| SCHEMBL7307710 | 0.84 | LMNA (0.50) | KMT2ALMNACHRM3NPY2R | |
| Hydrochloric Acid SCHEMBL7309309 | 0.79 | KDM1A (0.42) | GRIN2BKMT2AHTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7370551 | 0.79 | TSHR (0.40) | CRBNALDH1A1HTR1AHTR2APDE3B | |
| SCHEMBL7288177 | 0.77 | GRIN2B (0.57) | GRIN2BCRBNALDH1A1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL7371616 | 0.75 | HTR1A (0.47) | ALDH1A1HTR1ADRD4HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL7292922 | 0.74 | CHRM2 (0.59) | KMT2ALMNACHRM3NPY2R | |
| SCHEMBL9312162 | 0.74 | CYP1A2 (0.45) | CRBNALDH1A1PDE3BPDE3A | |
| SCHEMBL7328182 | 0.74 | GRIN2B (0.62) | GRIN2BCRBNHTR1ADRD4HTR2A | |
| SCHEMBL9308929 | 0.72 | KDM1A (0.52) | HTR1ADRD4HTR2AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306719-A | Cardiotonic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0255134-B1 | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5071856-A | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0255134-A2 | Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |