Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.42 |
| ▸ | DRD4 | P21917 | 15/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319126 | 0.90 | HRH3 (0.41) | DRD2DRD4 | |
| SCHEMBL7324501 | 0.88 | DRD2 (0.38) | DRD2DRD4 | |
| SCHEMBL7317480 | 0.88 | CCR5 (0.51) | DRD2DRD4 | |
| SCHEMBL7323873 | 0.85 | ALDH1A1 (0.46) | DRD2DRD4SLC6A4 | |
| SCHEMBL7326142 | 0.83 | CCR5 (0.47) | DRD2DRD4SLC6A4 | |
| SCHEMBL7322205 | 0.81 | DRD2 (0.43) | DRD2DRD4 | |
| SCHEMBL7326195 | 0.76 | SLC6A4 (0.52) | SLC6A4 | |
| SCHEMBL3786167 | 0.74 | SLC6A2 (0.50) | SLC6A4 | |
| SCHEMBL27466550 | 0.73 | DRD2 (0.42) | DRD2 | |
| SCHEMBL8329993 | 0.73 | FFAR4 (0.37) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |