Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
| ▸ | DRD4 | P21917 | 9/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326142 | 0.90 | CCR5 (0.47) | CCR5DRD2DRD4SLC6A2SLC6A4 | |
| SCHEMBL7317480 | 0.87 | CCR5 (0.51) | CCR5DRD2DRD4 | |
| SCHEMBL7319083 | 0.85 | DRD2 (0.42) | DRD2DRD4SLC6A4 | |
| SCHEMBL7319126 | 0.81 | HRH3 (0.41) | ALDH1A1DRD2DRD4 | |
| SCHEMBL7325823 | 0.79 | SIGMAR1 (0.47) | ALDH1A1MAPTSIGMAR1 | |
| SCHEMBL7324501 | 0.79 | DRD2 (0.38) | DRD2DRD4HTR1A | |
| SCHEMBL7322205 | 0.78 | DRD2 (0.43) | ALDH1A1KDM4EMAPTDRD2DRD4 | |
| SCHEMBL8329993 | 0.76 | FFAR4 (0.37) | CCR5SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL7325720 | 0.76 | ABCB1 (0.60) | CCR3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL30493951 | 0.76 | ABCB1 (0.60) | CCR3SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |