Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | MFN2 | O95140 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322425 | 0.81 | SLC6A4 (0.41) | TMEM97SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7326142 | 0.81 | CCR5 (0.47) | CCR5SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7319768 | 0.79 | SLC6A4 (0.45) | TMEM97SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7323873 | 0.76 | ALDH1A1 (0.46) | SIGMAR1CCR5SLC6A2SLC6A4 | |
| SCHEMBL7317480 | 0.75 | CCR5 (0.51) | CCR5 | |
| SCHEMBL7325407 | 0.74 | SLC6A4 (0.41) | TMEM97SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7319083 | 0.73 | DRD2 (0.42) | SLC6A4 | |
| SCHEMBL7323813 | 0.73 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL7315921 | 0.73 | APP (0.41) | FFAR4SLC6A4SLC6A3 | |
| SCHEMBL7326195 | 0.72 | SLC6A4 (0.52) | TMEM97SIGMAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |