Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313183 | 0.89 | FFAR1 (0.41) | HPGDSIGMAR1KMOHRH3ACMSD | |
| Hydrochloric Acid SCHEMBL7319313 | 0.88 | FFAR1 (0.40) | HPGDSIGMAR1KMOHRH3ACMSD | |
| SCHEMBL7315840 | 0.81 | CEL (0.38) | SIGMAR1KMOCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7324554 | 0.78 | TSHR (0.40) | NPC1RAB9A | |
| SCHEMBL7317851 | 0.77 | HDAC8 (0.46) | HPGDSIGMAR1KMOSMN1; SMN2HRH3 | |
| SCHEMBL8579966 | 0.74 | SLC6A2 (0.41) | KMOCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7346168 | 0.71 | OPRL1 (0.38) | SIGMAR1KMOACMSDSLC9A1 | |
| SCHEMBL7312887 | 0.71 | FFAR1 (0.44) | HPGDKMOACMSDSLC9A1FFAR1 | |
| Hydrochloric Acid SCHEMBL7315858 | 0.70 | FFAR1 (0.43) | HPGDKMOACMSDFFAR1 | |
| SCHEMBL7319310 | 0.69 | PTGDR2 (0.34) | NPC1RAB9AKMOSMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |