Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9551319 | 0.87 | CTSS (0.52) | CTSLCTSKCTSBCTSSITGB3 | |
| SCHEMBL8083427 | 0.83 | TACR1 (0.71) | TACR1CTSLCTSKCTSBCTSS | |
| SCHEMBL7319476 | 0.83 | CTSL (0.52) | TACR1CTSLCTSKCTSBCTSS | |
| SCHEMBL8088245 | 0.82 | ALDH1A1 (0.60) | TACR1CTSLCTSKCTSBCTSS | |
| Alanine SCHEMBL5482606 | 0.81 | ITGB3 (0.59) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL7585707 | 0.78 | TP53 (0.62) | ALDH1A1 | |
| SCHEMBL8785257 | 0.77 | ALDH1A1 (0.74) | TACR1CTSLCTSKCTSBCTSS | |
| SCHEMBL8785267 | 0.77 | ALDH1A1 (0.74) | TACR1CTSLCTSKCTSBCTSS | |
| SCHEMBL7285798 | 0.77 | ALDH1A1 (0.74) | TACR1CTSLCTSKCTSBCTSS | |
| SCHEMBL7215150 | 0.77 | TACR1 (0.56) | TACR1CTSLCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |