Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319482 | 0.83 | TACR1 (0.53) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL4064899 | 0.79 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL7343973 | 0.77 | CAPN1 (0.55) | CTSLCTSKCTSBCTSSALDH1A1 | |
| Phosphonic Acid SCHEMBL7620939 | 0.76 | ALDH1A1 (0.62) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL8083427 | 0.76 | TACR1 (0.71) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL7248994 | 0.76 | NPC1 (0.59) | — | |
| Valine SCHEMBL5917274 | 0.75 | ITGB3 (0.59) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL764062 | 0.74 | CTSL (0.68) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL6387189 | 0.74 | CTSL (0.68) | CTSLCTSKCTSBCTSSALDH1A1 | |
| SCHEMBL10250520 | 0.74 | CTSL (0.68) | CTSLCTSKCTSBCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |