Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.40 |
| ▸ | MMP9 | P14780 | 14/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 12/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420109 | 0.92 | MMP1 (0.41) | MMP1MMP9POLBRXFP1MMP3 | |
| SCHEMBL7329953 | 0.82 | MMP1 (0.50) | MMP1MMP9POLBRXFP1MMP3 | |
| SCHEMBL7322384 | 0.76 | MMP1 (0.54) | MMP1MMP9MMP3REN | |
| SCHEMBL9349379 | 0.74 | CYP1B1 (0.46) | MMP1MMP9MMP3 | |
| SCHEMBL7323279 | 0.74 | MMP9 (0.52) | MMP1MMP9POLBMMP3 | |
| SCHEMBL7323303 | 0.74 | MMP9 (0.52) | MMP1MMP9POLBMMP3 | |
| SCHEMBL7323291 | 0.74 | MMP9 (0.52) | MMP1MMP9POLBMMP3 | |
| SCHEMBL7356722 | 0.72 | ECE1 (0.49) | — | |
| SCHEMBL7329563 | 0.72 | CYP1B1 (0.45) | MMP1MMP9POLBRXFP1MMP3 | |
| SCHEMBL7324972 | 0.71 | MMP1 (0.45) | MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |