Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.50 |
| ▸ | MMP9 | P14780 | 16/20 | 0.50 |
| ▸ | MMP3 | P08254 | 13/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323291 | 0.91 | MMP9 (0.52) | MMP1MMP9MMP3POLBMEN1 | |
| SCHEMBL7323303 | 0.91 | MMP9 (0.52) | MMP1MMP9MMP3POLBMEN1 | |
| SCHEMBL7323279 | 0.91 | MMP9 (0.52) | MMP1MMP9MMP3POLBMEN1 | |
| SCHEMBL9349379 | 0.91 | CYP1B1 (0.46) | MMP1MMP9MMP3 | |
| SCHEMBL7329563 | 0.88 | CYP1B1 (0.45) | MMP1MMP9MMP3POLBRXFP1 | |
| SCHEMBL7322384 | 0.84 | MMP1 (0.54) | MMP1MMP9MMP3 | |
| SCHEMBL7356722 | 0.83 | ECE1 (0.49) | — | |
| SCHEMBL7319486 | 0.82 | MMP1 (0.40) | MMP1MMP9MMP3POLBRXFP1 | |
| SCHEMBL7357542 | 0.79 | MMP1 (0.55) | MMP1MMP9MMP3KDM4E | |
| SCHEMBL7324972 | 0.78 | MMP1 (0.45) | MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |