Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 17/20 | 0.52 |
| ▸ | MMP1 | P03956 | 16/20 | 0.52 |
| ▸ | MMP3 | P08254 | 14/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323279 | 1.00 | MMP9 (0.52) | MMP9MMP1MMP3MMP2ADAM17 | |
| SCHEMBL7323291 | 1.00 | MMP9 (0.52) | MMP9MMP1MMP3MMP2ADAM17 | |
| SCHEMBL7329953 | 0.91 | MMP1 (0.50) | MMP9MMP1MMP3MEN1POLB | |
| SCHEMBL7329563 | 0.87 | CYP1B1 (0.45) | MMP9MMP1MMP3MEN1POLB | |
| SCHEMBL9349379 | 0.84 | CYP1B1 (0.46) | MMP9MMP1MMP3 | |
| SCHEMBL7322283 | 0.84 | MMP1 (0.54) | MMP9MMP1MMP3MMP2 | |
| SCHEMBL7322291 | 0.84 | MMP1 (0.54) | MMP9MMP1MMP3MMP2 | |
| SCHEMBL7322317 | 0.83 | MMP1 (0.47) | MMP9MMP1MMP3MMP2 | |
| SCHEMBL7322384 | 0.78 | MMP1 (0.54) | MMP9MMP1MMP3MMP2 | |
| SCHEMBL7356722 | 0.77 | ECE1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |