Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 8/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876094 | 0.76 | CA12 (0.44) | ELANEMEN1KMT2AHTTFABP3 | |
| SCHEMBL7176770 | 0.74 | FABP3 (0.38) | ELANEMEN1KMT2AHTTFABP3 | |
| SCHEMBL27844473 | 0.70 | IDO1 (0.48) | MEN1RAB9AKMT2AABCB1HTT | |
| SCHEMBL5580077 | 0.70 | LTA4H (0.57) | NPC1RAB9AKMT2AHTT | |
| SCHEMBL19172033 | 0.70 | MAPT (0.42) | NPC1RAB9AHTTL3MBTL1 | |
| SCHEMBL8604700 | 0.69 | CYP1A1 (0.59) | — | |
| SCHEMBL7358780 | 0.69 | ITGB1 (0.48) | ITGB1ITGA4 | |
| SCHEMBL8712652 | 0.69 | MAOB (0.48) | KMT2AHTTTAAR1 | |
| SCHEMBL10053930 | 0.68 | NAAA (0.48) | MEN1NPC1RAB9AKMT2AITGB1 | |
| SCHEMBL8710305 | 0.68 | TRPA1 (0.50) | NPC1RAB9AKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403584-B1 | CONJUNCTIVITIS, ALLERGIC RHINITIS, ALZHEIMER'S DISEASE, ASTHMA, ATHEROSCLEROSIS, AUTOLOGOUS BONE MARROW TRANSPLANTATION, ANTIINFLAMMATORY, ETC | MERCK & CO., INC. | 2002-06-11 | — | — | US | disclosed |