Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650084 | 0.87 | MMP8 (0.47) | MMP8TSHRALDH1A1PPIDMEN1 | |
| SCHEMBL27568984 | 0.86 | SLC15A1 (0.53) | ALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL902140 | 0.84 | ABCB1 (0.47) | ALDH1A1MEN1KMT2ANPC1LMNA | |
| SCHEMBL18065659 | 0.81 | MMP8 (0.53) | MMP8TSHRALDH1A1PPIDMEN1 | |
| SCHEMBL7328940 | 0.80 | CYP1A2 (0.43) | MEN1KMT2ANPC1POLBMME | |
| SCHEMBL12268225 | 0.80 | TRPA1 (0.53) | MMP8TSHRALDH1A1PPIDMEN1 | |
| SCHEMBL12446348 | 0.80 | MMP8 (0.51) | MMP8TSHRALDH1A1PPIDMEN1 | |
| SCHEMBL5837006 | 0.80 | TRPA1 (0.53) | MMP8TSHRALDH1A1PPIDMEN1 | |
| SCHEMBL31448302 | 0.80 | TRPA1 (0.53) | MMP8TSHRALDH1A1PPIDMEN1 | |
| SCHEMBL1915970 | 0.79 | CPA3 (0.56) | LTA4HMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079648-A | Preparation contains the method for the pharmaceutical composition of imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1993-12-22 | — | — | CN | disclosed |
| CN-1048039-A | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1990-12-26 | — | — | CN | disclosed |
| EP-0327877-A2 | Peptide-renininhibitors | MERCK PATENT GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0292800-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |