Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323685 | 0.91 | LMNA (0.47) | ALDH1A1ITGB3ITGA2BLMNAKMT2A | |
| SCHEMBL7351149 | 0.87 | ITGB3 (0.43) | RAB9AALDH1A1ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7320112 | 0.85 | ITGB3 (0.61) | RAB9AALDH1A1ITGB3ITGA2B | |
| SCHEMBL7389607 | 0.82 | ITGB3 (0.50) | ALDH1A1ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7323479 | 0.81 | RAB9A (0.40) | RAB9AALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL7378676 | 0.80 | ITGB3 (0.49) | ALDH1A1ITGB3ITGA2BPLA2G2ALMNA | |
| SCHEMBL7357417 | 0.79 | ITGB3 (0.46) | ALDH1A1ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7348963 | 0.79 | ITGB3 (0.50) | ITGB3ITGA2BPLA2G2AHDAC1 | |
| SCHEMBL7353690 | 0.78 | ITGB3 (0.43) | ITGB3ITGA2BPLA2G2ALMNAKMT2A | |
| SCHEMBL7381804 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | claimed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | claimed |
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |