Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 7/20 | 0.47 |
| ▸ | HPN | P05981 | 6/20 | 0.42 |
| ▸ | PLAU | P00749 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323479 | 0.86 | RAB9A (0.40) | PLAURAB9APLAT | |
| SCHEMBL7320112 | 0.80 | ITGB3 (0.61) | F2HPNPLAUITGB3ITGA2B | |
| SCHEMBL9485345 | 0.77 | HPN (0.47) | F10F2HPNPLAUITGB3 | |
| SCHEMBL8971449 | 0.73 | ITGB3 (0.57) | F10F2HPNPLAUITGB3 | |
| SCHEMBL7390380 | 0.73 | ITGB3 (0.64) | F10F2PLAUITGB3ITGA2B | |
| SCHEMBL9710588 | 0.73 | ITGB3 (0.64) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL7387875 | 0.73 | ITGB3 (0.76) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL7318568 | 0.73 | ITGB3 (0.58) | F2ITGB3ITGA2B | |
| SCHEMBL7380948 | 0.71 | ITGB3 (0.60) | F10F2ITGB3ITGA2BST14 | |
| SCHEMBL6816537 | 0.71 | PLAU (0.73) | F10F2HPNPLAUST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |